The best ergonomic mouse for 2025

A mouse may seem like a small consideration for your workstation setup. But after you’ve addressed the crucial ergonomics — raising your monitor to eye-level, using the right keyboard and taking frequent breaks throughout your workdays — it’s a good idea to make sure the mouse you use is comfortable as well. People dealing with conditions like carpal tunnel and wrist pain may be interested in finding the best ergonomic mouse for them. Vertical and semi-vertical designs turn your palm towards your midline instead of downwards, creating a handshake position that may feel more natural. Others employ a trackball to minimize the work your shoulder has to do in a day. I tested out more than 20 highly regarded ergonomic mice to come up with recommendations for vertical, semi-vertical, trackball and more, along with advice about the merits of the different ergonomic designs.

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